Acute Necrotizing Encephalitis (Of Childhood), a Blood-Brain Barrier Perspective.

Here we present a blog post about ANE from The Blood-Brain Barrier Scientist

A blog about blood-brain barrier, science, metal, old-school gaming and other geeky stuff.



It is a condition that was firstly discovered by Mizuguchi and colleagues in 1995 firstly described in infants and toddlers ( It was firstly described in patients from Asian origin (Japan). It was initially described to occur during the winter period, in particular with region that had experienced an influenza A outbreak. The main clinical feature of the disease marked by the presence in the magnetic resonance imaging (MRI) of increased water content inside the brain, mostly associated with edema (brain swelling). This increased water content can only be explained by the opening of the blood-brain barrier.

Excerpt was from the following post on   to continue reading the rest of this quite fascinating and informative blog post see:

#ANEawarenessday #virus #cytokinestorm #braininjury #AcuteNecrotizingEncephalopathy  #ANEandScience 


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PANDAS/PANS Awareness Day

Every October 9th is  Awareness Day to spread awareness far and wide. Each year, we increase awareness and understanding about ,

PANDAS stands for pediatric autoimmune neuropsychiatric disorders associated with streptococcus. The syndrome involves sudden and often major changes in personality, behavior, and movement in children following an infection involving Streptococcus infection.


Who doesn’t love a free event?

Here’s your chance to make connections with individuals in many fields.

#RareFest2018 #ANEAwareness #NOTjusttheflu

Cambridge Rare Disease Network (CRDN) is a charity building a regional community to address the unmet needs of those living with rare conditions, their families and the professionals who work with them.  Our vision is for a united regional voice underpinning the development of services and treatments.

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