What is ANE?
Acute Necrotizing Encephalopathy is a disease characterized by encephalopathy ensued by varying degrees of brain injury. ANE usually follows an acute, mostly viral, infection. Influenza is the leading associated virus. The symptoms of the viral infection (fever, respiratory infection, and gastroenteritis, among others) are followed by seizures, disturbance of consciousness that may rapidly progress to a coma, liver problems and neurological deficits.