Acute Necrotizing Encephalopathy’s major trigger is influenza. So much is unknown about the causation of this disease and why some RANBP2 carriers are affected while other go on with no effects at all,

Here are some interesting point made about the flu in the articled linked below :

 “We always wondered why some people can effectively control viral infections while others succumb to the disease,” says Kedzierska. To investigate this — and why the 1918 outbreak was so virulent — Kedzierska, van de Sandt and Dr. Kirsty Short of Australia’s University of Queensland reviewed a large number of influenza studies.

This year marks the centenary of the 1918 influenza pandemic, the worst flu outbreak in recorded history. A new study into the human, viral and societal factors behind its severity provides valuable lessons that could save lives in future pandemics. Publishing in Frontiers in Cellular and Infection Microbiology, the authors warn that while the world is better prepared than 100 years ago, new challenges will affect the impact of the next influenza virus pandemic — including changing population demographics, antibiotic resistance and climate change.




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