Acute Necrotizing Encephalitis (Of Childhood), a Blood-Brain Barrier Perspective.

Here we present a blog post about ANE from The Blood-Brain Barrier Scientist

A blog about blood-brain barrier, science, metal, old-school gaming and other geeky stuff.



It is a condition that was firstly discovered by Mizuguchi and colleagues in 1995 firstly described in infants and toddlers ( It was firstly described in patients from Asian origin (Japan). It was initially described to occur during the winter period, in particular with region that had experienced an influenza A outbreak. The main clinical feature of the disease marked by the presence in the magnetic resonance imaging (MRI) of increased water content inside the brain, mostly associated with edema (brain swelling). This increased water content can only be explained by the opening of the blood-brain barrier.

Excerpt was from the following post on   to continue reading the rest of this quite fascinating and informative blog post see:

#ANEawarenessday #virus #cytokinestorm #braininjury #AcuteNecrotizingEncephalopathy  #ANEandScience 


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